GLP-1 pricing · every dose
GLP-1 prices by dose: compounded tirzepatide & semaglutide, all-in
Compounded tirzepatide costs $120.14 a month on the 3-month auto-refill plan at 2.5 mg a week, billed $360.40 every 12 weeks, or $174 to $269 for a one-month (4-week) supply bought one time (2.5 mg to 15 mg a week). Compounded semaglutide costs $96.05 a month on the 3-month starter pack (0.25 → 0.5 → 1 mg weekly) with auto-refill, billed $288.15 per pack, the same price every time you order it, or $169 to $199 for a one-month (4-week) supply bought one time (0.25 mg to 2.4 mg a week).
Every price is all-in: the medication, a licensed provider’s review, syringes and alcohol prep pads, and cold shipping. There is no membership fee. You are charged at checkout, and if a provider does not approve treatment, you get a full refund.
Compounded tirzepatide price per month, by dose
Compounded tirzepatide costs $174 to $269 a month bought one month at a time, $147.90 to $228.65 a month on auto-refill every 4 weeks, and $120.14 to $162.64 a month on the 3-month auto-refill plan (billed every 12 weeks), from 2.5 mg to 15 mg a week. A 3-month supply bought one time saves $98–$233 against three one-month orders, and auto-refill takes another 15% off.
| Weekly dose | 1 month, one-time | 1 month, auto-refill | 3 months, one-time | 3 months, auto-refill | Per month on 3-month auto-refill |
|---|---|---|---|---|---|
| 2.5 mg / week | $174 | $147.90every 4 weeks | $424$141.34/mo | $360.40every 12 weeks | $120.14/mo |
| 5 mg / week | $209 | $177.65every 4 weeks | $454$151.34/mo | $385.90every 12 weeks | $128.64/mo |
| 7.5 mg / week | $224 | $190.40every 4 weeks | $484$161.34/mo | $411.40every 12 weeks | $137.14/mo |
| 10 mg / week | $239 | $203.15every 4 weeks | $514$171.34/mo | $436.90every 12 weeks | $145.64/mo |
| 12.5 mg / week | $254 | $215.90every 4 weeks | $544$181.34/mo | $462.40every 12 weeks | $154.14/mo |
| 15 mg / week | $269 | $228.65every 4 weeks | $574$191.34/mo | $487.90every 12 weeks | $162.64/mo |
Compounded semaglutide price per month, by dose
Compounded semaglutide costs $169 to $199 a month bought one month at a time, $143.65 to $169.15 a month on auto-refill every 4 weeks, and $105.97 to $127.22 a month on the 3-month auto-refill plan (billed every 12 weeks), from 0.25 mg to 2.4 mg a week. A 3-month supply bought one time saves $133–$148 against three one-month orders, and auto-refill takes another 15% off.
| Weekly dose | 1 month, one-time | 1 month, auto-refill | 3 months, one-time | 3 months, auto-refill | Per month on 3-month auto-refill |
|---|---|---|---|---|---|
| 0.25 mg / week | $169 | $143.65every 4 weeks | $374$124.67/mo | $317.90every 12 weeks | $105.97/mo |
| 0.5 mg / week | $174 | $147.90every 4 weeks | $379$126.34/mo | $322.15every 12 weeks | $107.39/mo |
| 1 mg / week | $179 | $152.15every 4 weeks | $399$133/mo | $339.15every 12 weeks | $113.05/mo |
| 1.7 mg / week | $189 | $160.65every 4 weeks | $429$143/mo | $364.65every 12 weeks | $121.55/mo |
| 2.4 mg / week | $199 | $169.15every 4 weeks | $449$149.67/mo | $381.65every 12 weeks | $127.22/mo |
A one-month supply is 4 once-weekly doses (28 days); a 3-month supply is 12 doses (84 days), shipped together. "Per month" on a 3-month supply is its price divided by 3; it is billed as one charge. The dose you choose is a request; the licensed provider who reviews your intake sets the dose you are prescribed.
Which plan is the best value?
Of our own plans, the 3-month supply with auto-refill costs the least per month at every dose. Compounded tirzepatide on the 3-month auto-refill plan is $120.14 to $162.64 a month (2.5 mg to 15 mg), billed $360.40 to $487.90 every 12 weeks.
Compounded semaglutide on the 3-month auto-refill plan is $105.97 to $127.22 a month (0.25 mg to 2.4 mg), billed $317.90 to $381.65 every 12 weeks; the 3-month starter pack is lower still, at $96.05 a month ($288.15 per pack, and it can be re-ordered at the same price).
If you would rather not subscribe, a 3-month supply bought one time still costs less per month than buying one month at a time, and it does not renew.
Starter protocols
Starter protocols are 3-month supplies with a set weekly dose for each month, at one price. A provider decides whether a starter protocol is right for you.
| Protocol | 3 months, one-time | 3 months, auto-refill | After the protocol, with auto-refill |
|---|---|---|---|
| Compounded tirzepatide2.5 → 5 → 7.5 mg weeklyThe standard 3-month titration — dose steps up each month, one price, titration included. | $439$146.34/mo | $373.15$124.39/mo | Re-order this pack at the same price, or with auto-refill, refills continue at 7.5 mg a week (unless your provider changes your dose) for $411.40 every 12 weeks. The difference from the starter price is charged only after you confirm it at your first refill check-in. |
| Compounded tirzepatide10 → 12.5 → 15 mg weeklyContinuation protocol — for stepping up in months 4–6. | $539$179.67/mo | $458.15$152.72/mo | Re-order this pack at the same price, or with auto-refill, refills continue at 15 mg a week (unless your provider changes your dose) for $487.90 every 12 weeks. The difference from the starter price is charged only after you confirm it at your first refill check-in. |
| Compounded tirzepatide15 mg weekly × 3 monthsTop-dose protocol — established patients at the maximum weekly dose. | $574$191.34/mo | $487.90$162.64/mo | Re-order this pack at the same price, or with auto-refill, refills continue at 15 mg a week (unless your provider changes your dose) for $487.90 every 12 weeks. |
| Compounded semaglutide0.25 → 0.5 → 1 mg weeklyThe standard 3-month titration — dose steps up each month, one price, titration included. | $339$113/mo | $288.15$96.05/mo | Re-order this pack at the same price, or with auto-refill, refills continue at 1 mg a week (unless your provider changes your dose) for $339.15 every 12 weeks. The difference from the starter price is charged only after you confirm it at your first refill check-in. |
| Compounded semaglutide1.7 → 2.4 → 2.4 mg weeklyContinuation protocol — for stepping up after your first months. | $449$149.67/mo | $381.65$127.22/mo | Re-order this pack at the same price, or with auto-refill, refills continue at 2.4 mg a week (unless your provider changes your dose) for $381.65 every 12 weeks. |
| Compounded semaglutide2.4 mg weekly × 3 monthsTop-dose protocol — established patients at the maximum weekly dose. | $449$149.67/mo | $381.65$127.22/mo | Re-order this pack at the same price, or with auto-refill, refills continue at 2.4 mg a week (unless your provider changes your dose) for $381.65 every 12 weeks. |
Compounded tirzepatide starter pack price · Compounded semaglutide starter pack price
What every price includes
- The medicationCompounded tirzepatide or semaglutide, prepared by a licensed U.S. compounding pharmacy for your prescription.
- Licensed provider reviewA licensed provider in our partner provider network reviews your health intake. There is no separate consultation fee.
- Syringes and alcohol prep padsSyringes and alcohol prep pads are included with every order.
- Cold shippingShipped cold from a licensed U.S. pharmacy in discreet packaging, with tracking. No shipping fee.
- Care-team messagingMessage your care team from your patient portal at any time.
- No membership feeNo membership and no program fee. The price of your dose and supply is the whole price.
How billing works
One-time purchases never renew
A one-time purchase is billed once at checkout and ends after delivery. It does not auto-renew and nothing is charged later. You can buy one month at a time, as often as you choose.
Auto-refill is optional
Subscribe & Save takes 15% off and is only on if you choose it at checkout. Each refill is charged before your current supply runs out, timed to the delivery of your last box: about every 4 weeks (28 days) on a 1-month supply, or about every 12 weeks (84 days) on a 3-month supply. A provider reviews each refill. Pause or cancel anytime from your patient portal, with no fee.
Charged at checkout, full refund if not approved
You pay when you check out. A licensed provider then reviews your intake. If the provider does not approve treatment, your payment is refunded in full; allow 5–10 business days for the refund to appear, depending on your bank.
Changing your dose
You pay the listed price of the dose and supply you choose at checkout. An auto-refill renews at the plan price set at checkout (for a starter protocol, the continuation price listed beside it). If you ask to move up a dose at a refill check-in, you see the price difference and confirm it before it is charged. There is no separate program charge.
Available in all 50 states
Approved prescriptions for compounded GLP-1 injections ship from a licensed U.S. pharmacy to all 50 states. A provider licensed in your state, from our partner provider network, reviews your online health intake and prescribes only if treatment is appropriate. There is no appointment to schedule to get started. Depending on your state and health history, a provider may require a video visit before prescribing.
About Affinity Direct
Affinity Direct is the online division of Affinity Whole Health, a Midwest clinic network founded in 2012 with 4 locations and more than 10,000 patients. Weight-loss intakes are reviewed by licensed clinicians in our partner provider network.
Brand-name GLP-1 prices without insurance
Compounded tirzepatide and semaglutide are not FDA-approved and are not the same products as Zepbound or Wegovy; the FDA has not reviewed them for safety, effectiveness or quality. Zepbound and Wegovy are FDA-approved brand-name medicines that can be bought self-pay from their manufacturers. The prices below come from the manufacturers’ own pages on the dates shown and cover the medicine only: the prescription, and any provider visit to get one, are separate.
| Medicine | Self-pay price | Terms | Source · checked |
|---|---|---|---|
| Zepbound vials (LillyDirect self-pay)Brand-name, FDA-approved | $299–$699 a month | $299 a month at 2.5 mg and $399 at 5 mg. At 7.5–15 mg: $449 a month when you refill within 45 days, otherwise $499 at 7.5 mg and $699 at 10, 12.5 and 15 mg. A month is 28 days and 4 single-dose vials. Needles and syringes are bought separately, and the prescription comes from your own provider. Self-pay only; eligibility required, terms and conditions apply. | lilly.comOctober 17, 2026 |
| Wegovy pen (NovoCare Pharmacy self-pay)Brand-name, FDA-approved | $199–$349 a month | $199 a month for a new patient’s first 2 monthly fills of 0.25 or 0.5 mg (offer through December 31, 2026), then $349 a month at 0.25, 0.5, 1, 1.7 and 2.4 mg. Wegovy HD 7.2 mg is $399 a month. A month is one box of 4 pens. NovoCare says its pricing will be updated after December 31, 2026. Self-pay through NovoCare Pharmacy with a valid prescription; the provider visit is separate. | novocare.comOctober 17, 2026 |
| Wegovy pill (NovoCare Pharmacy self-pay)Brand-name, FDA-approved | $149–$299 a month | $149 a month at 1.5 mg, $199 at 4 mg, $299 at 9 mg and 25 mg. A month is one bottle of 30 tablets. Self-pay through NovoCare Pharmacy with a valid prescription; the provider visit is separate. | novocare.comOctober 17, 2026 |
A licensed provider decides which medication, if any, is appropriate for you. Manufacturer prices change; check the manufacturer’s page before you buy.
GLP-1 pricing questions
Is there a membership fee?
No. There is no membership fee, no consultation fee and no shipping fee. The price of the dose you choose is the whole price: the medication, a licensed provider’s review, syringes and alcohol prep pads, and cold shipping.
Can I buy one month at a time?
Yes. Every dose can be bought as a one-month supply, one time, with no subscription. One month of compounded tirzepatide is $174 to $269 and one month of compounded semaglutide is $169 to $199, depending on the weekly dose. A one-time purchase is billed once and does not auto-renew.
Are supplies and shipping included?
Yes. Syringes and alcohol prep pads come with every order, and the medication ships cold from a licensed U.S. pharmacy in discreet packaging, with tracking, at no extra charge.
What if a provider does not prescribe?
You get a full refund. You are charged at checkout; if the licensed provider who reviews your intake does not approve treatment, your payment is refunded in full (allow 5–10 business days for it to appear).
Do you ship to all 50 states?
Yes. Affinity Direct serves all 50 states. A provider licensed in your state, from our partner provider network, reviews your intake, and approved prescriptions ship from a licensed U.S. pharmacy.
How much is tirzepatide 2.5 mg / 15 mg per month?
Compounded tirzepatide at 2.5 mg a week is $174 for a one-month supply bought one time, $147.90 a month on auto-refill every 4 weeks, or $120.14 a month on the 3-month auto-refill plan (billed $360.40 every 12 weeks). At 15 mg a week it is $269 for a one-month supply bought one time, $228.65 a month on auto-refill every 4 weeks, or $162.64 a month on the 3-month auto-refill plan (billed $487.90 every 12 weeks). Medication, provider review, supplies and cold shipping are included in every price.
Does the 3-month plan cost less?
Yes, per month. Bought one time, a 3-month supply saves $98–$233 on compounded tirzepatide and $133–$148 on compounded semaglutide against three one-month orders, depending on the dose. Choosing auto-refill takes another 15% off, which brings the lowest price to $120.14 a month for tirzepatide (2.5 mg a week) and $96.05 a month for semaglutide (the 3-month starter pack, which can be re-ordered at the same price). A 3-month supply is billed as one charge, and on auto-refill it renews every 12 weeks.
More on GLP-1 pricing
- Compounded tirzepatide How it works, who it is for, and the dose-by-dose buy box.
- Compounded semaglutide How it works, who it is for, and the dose-by-dose buy box.
- No membership, one month at a time How buying one month at a time works, with no membership fee.
- Tirzepatide prices compared Our price beside other online programs, read from each brand’s own page.
- Open price file (JSON) Every dose, both bases, dated and licensed CC BY 4.0. Also as CSV.
CSV version: glp1-prices.csv
Medical disclosure
Important safety information: Compounded semaglutide and compounded tirzepatide are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Prescription weight-loss medication is only available if a licensed provider determines it is appropriate for you after reviewing your health intake — your dose selection is a request, and the provider sets the actual dose. Individual results vary and no amount of weight loss is guaranteed. GLP-1-class medications should be used alongside a reduced-calorie diet and increased physical activity.
Next step
See if a GLP-1 is right for you
The eligibility check is free and takes a few minutes. You pay only when you choose a plan, and you get a full refund if a provider does not approve treatment.
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