South Dakota
Weight loss, peptide therapy and ED treatment, prescribed in South Dakota
A South Dakota-licensed provider reviews your intake, usually within 24 hours — then it ships free, in plain packaging, to Sioux Falls, Rapid City, Aberdeen and everywhere else in the Mount Rushmore State.
Five-minute intake · Free 2-day discreet shipping · Refunded if not approved
Weight loss
From $96.05/mo
Peptides
From $98.89/mo
ED
From $0.76/day
As seen & heard on
What you can start
in South Dakota
Every line is prescribed by South Dakota-licensed providers and ships free in two days.
GLP-1 weight loss
Semaglutide & Tirzepatide in South Dakota
From $96.05/mo
lowest Subscribe & Save monthly rate
Compounded semaglutide and tirzepatide, prescribed only when a licensed South Dakota provider decides it is appropriate for you.
- BMI 21+ — no comorbidity requirement
- Dose changes stay with your provider, not a call center
- Refunded in full if not approved
Peptide therapy
Glutathione, Sermorelin & NAD+ in South Dakota
From $98.89/mo
lowest effective monthly rate on Subscribe & Save
Glutathione, sermorelin, NAD+, MIC + B12 and PT-141 — reviewed by a licensed provider and dispensed by a compounding pharmacy, with injection supplies included at no charge.
- Free syringes and alcohol prep pads
- Subscribe & Save 15% on refills
- Refunded in full if not approved
ED treatment
Sildenafil & Tadalafil in South Dakota
From $0.76/day
daily tadalafil, 180-day Subscribe & Save
The same FDA-approved generics a pharmacy dispenses, at a fraction of the counter price. A five-minute intake, no appointment, and no conversation at a pharmacy counter.
- Retail pharmacies charge around $70 a dose
- Provider review, typically under 24 hours
- One-time or auto-refill — cancel anytime
Not sure which is right for you? Ask the Wellness Advisor
How it works
in South Dakota
Answer the health intake
About five minutes, from your phone — your history, your medications, and what you want to change.
A South Dakota-licensed provider reviews it
A clinician the South Dakota Board of Medical and Osteopathic Examiners licenses reads it and decides, usually within 24 hours. No appointment, no video call.
It ships free, discreetly
Plain packaging, free 2-day delivery anywhere in South Dakota, with injection supplies included where they are needed.
Five-minute intake · Free 2-day discreet shipping · Refunded if not approved
Licensed providers in all 50 states · 4 Midwest clinic locations
A real clinic, licensed to treat you in South Dakota
Your intake is read by a clinician licensed to practice in South Dakota through Affinity's partner provider network — that license is what makes the prescription legal here. There is no Affinity office in South Dakota, and none is needed: the review, the prescription and every refill happen without an appointment, a video call or a waiting room.
Prescriptions written for South Dakota patients are issued under South Dakota law by a clinician the South Dakota Board of Medical and Osteopathic Examiners licenses. There is no appointment to book and no video call to join — a provider reads your written intake and answers, usually within 24 hours. We ship to Sioux Falls, Rapid City, Aberdeen, Brookings, Watertown and Mitchell, and to every other South Dakota address.
South Dakota questions,
answered
Can I get treatment online in South Dakota?
Yes. Affinity Direct treats patients in all 50 states, South Dakota included — GLP-1 weight loss, peptide therapy and ED treatment. You complete a written health intake, a licensed provider reviews it, and approved orders ship free on 2-day delivery to any SD address.
Who writes the prescription for a South Dakota patient?
A clinician licensed in South Dakota and accountable to the South Dakota Board of Medical and Osteopathic Examiners, through Affinity's licensed partner provider network. That license is what makes the prescription legal here — an office in South Dakota is not required and we do not have one. A declined order is refunded in full.
Do I need an appointment or a video visit in South Dakota?
No. A provider reads your written intake rather than booking a call, and usually answers within 24 hours. There is nothing to schedule and nowhere to sit, anywhere in South Dakota.
How fast does an order reach South Dakota?
Shipping is free 2-day delivery on every order, in plain unmarked packaging, to any address in South Dakota. Peptide and GLP-1 orders include the injection supplies for the course, so there is nothing to source separately.
What happens if a provider decides treatment is not appropriate?
You are refunded in full, and our team can walk you through next steps. You are charged at checkout so the pharmacy can fill the moment a provider approves — but nothing is kept if treatment is declined, and there is no consultation fee either way.
How much does treatment cost in South Dakota?
GLP-1 weight loss starts at $96.05/mo (lowest Subscribe & Save monthly rate), peptide therapy at $98.89/mo (lowest effective monthly rate on Subscribe & Save), and ED treatment at $0.76/day (daily tadalafil, 180-day Subscribe & Save). Provider review, injection supplies where they are needed, and 2-day shipping are included at no extra cost, and prices are the same in South Dakota as in every other state.
Are the medications FDA-approved?
The ED medications are FDA-approved generics — the same sildenafil and tadalafil a pharmacy dispenses. The GLP-1 and peptide treatments are compounded: they are prepared for an individual prescription by a state-licensed US compounding pharmacy, and compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality before they are dispensed. A licensed South Dakota provider decides whether any treatment is appropriate for you.
Is a membership or subscription required?
No. Every treatment can be bought one time. There is no membership fee and no separate consultation fee — the provider review is included in the price you see. The prices shown are the lowest Subscribe & Save rate; Subscribe & Save is optional on every line, takes at least 15% off, and can be cancelled at any time.
Care by city across South Dakota
Sioux Falls
Rapid City
Start in about five minutes
Answer a private health intake and a South Dakota-licensed provider reviews it — usually within 24 hours. You are charged at checkout and refunded in full if treatment is not appropriate for you.
Five-minute intake · Free 2-day discreet shipping · Refunded if not approved