South Dakota · the Mount Rushmore State
Online men's and women's health care in South Dakota
Weight loss, peptide therapy and ED treatment for Sioux Falls, Rapid City, Aberdeen, Brookings and everywhere else in the Mount Rushmore State — prescribed by South Dakota-licensed providers, shipped free in two days.
What South Dakota patients can start today

GLP-1 weight loss
Semaglutide & tirzepatide in South Dakota
From $96.05/mo
lowest Subscribe & Save monthly rate
Compounded semaglutide and tirzepatide, prescribed only when a licensed South Dakota provider determines it is appropriate. Dose changes stay with your provider, not a call centre.
- BMI 21+ — no comorbidity requirement
- Provider-led dose titration
- Free 2-day discreet shipping

Peptide therapy
Peptide protocols shipped to South Dakota
From $84.76/mo
lowest effective monthly rate on Subscribe & Save
Glutathione, sermorelin, NAD+, MIC + B12 and PT-141, reviewed by a licensed provider and dispensed by a compounding pharmacy. Injection supplies are included at no charge.
- Free syringes and alcohol prep pads
- Subscribe & Save 15% on refills
- Charged at checkout, refunded if declined

ED treatment
Sildenafil & tadalafil in South Dakota
From $0.76/day
daily tadalafil, 180-day Subscribe & Save
The same FDA-approved generics a pharmacy dispenses, at a fraction of the counter price. A five-minute intake, no appointment, and no conversation at a pharmacy counter.
- Retail pharmacies charge around $70 a dose
- Provider review, typically under 24 hours
- One-time or auto-refill — cancel anytime
Licensed South Dakota providers, reviewed within 24 hours
Your intake is read by a clinician licensed to practise in South Dakota through Affinity's partner provider network — that licence is what makes the prescription legal here. There is no Affinity office in South Dakota, and none is needed: the review, the prescription and every refill happen without an appointment, a video call or a waiting room.
Prescriptions written for South Dakota patients are issued under South Dakota law by a clinician the South Dakota Board of Medical and Osteopathic Examiners licenses. South Dakota permits asynchronous review, so there is no appointment to book and no video call to join.
Serving across SD
- Sioux Falls
- Rapid City
- Aberdeen
- Brookings
- Watertown
- Mitchell
Every SD address is served online. Affinity has no office in South Dakota, and none is needed to be prescribed here.
Care by city across South Dakota
Sioux Falls
Rapid City
Start in about five minutes
Answer a private health intake, and a South Dakota-licensed provider reviews it — usually the same day. You are charged at checkout and refunded in full if treatment is not appropriate for you.
