Compounded Semaglutide
A once-weekly GLP-1 injection that reduces appetite and helps you feel full sooner — prescribed and supervised by a licensed provider, cold-shipped monthly with supplies included.
Transparent pricing
Choose your tier
1–2 mg/mL
Semaglutide · Starter
The standard starting point for GLP-1 therapy
- New to GLP-1 medications
- Restarting after a break
- Prefer the lowest monthly cost
Charged at checkout · full refund if not approved
3.4–5 mg/mL
Semaglutide · Maintenance
For patients who have titrated up to higher weekly doses
- Already on a higher semaglutide dose
- Provider-guided dose increases
- Continuing an established program
Charged at checkout · full refund if not approved
The science
How it works
GLP-1 receptor agonist
Semaglutide mimics GLP-1, a hormone your gut releases after eating. It signals fullness to the brain, reduces appetite, and slows how quickly food leaves the stomach — so smaller meals satisfy you for longer.
Gradual weekly titration
Treatment starts at a low weekly dose and increases stepwise over several months as tolerated. Titrating slowly is how providers minimize the digestive side effects that come from raising the dose too fast.
Works with lifestyle change
GLP-1 therapy is studied and prescribed alongside a reduced-calorie diet and increased activity. The medication makes the behavior change sustainable — it does not replace it.
STEP 1 trial
~15% average body-weight loss
Wilding et al., NEJM (2021) — STEP 1
In the STEP 1 trial of the FDA-approved branded version (2.4 mg weekly alongside diet and exercise), adults lost an average of about 15% of body weight over 68 weeks. Individual results vary and no outcome is guaranteed; compounded semaglutide is a separate, non-FDA-approved preparation.
Safety first
Taking it safely
Administration basics
- Once-weekly subcutaneous self-injection, any consistent day of the week
- Inject into the abdomen, thigh, or upper arm; rotate sites
- Refrigerate the vial; supplies (syringes, alcohol prep pads) are included
- Your provider sets and adjusts your dose — never change it on your own
Common side effects
Nausea (most common, usually early or after dose increases) · Constipation or diarrhea · Reduced appetite · Fatigue · Injection-site irritation
When to contact a provider
- Severe or persistent abdominal pain (possible pancreatitis) — seek care promptly
- Symptoms of gallbladder problems (right-upper abdominal pain, fever, jaundice)
- Severe vomiting or diarrhea leading to dehydration
- Signs of an allergic reaction (swelling, trouble breathing) — call 911
This is educational information, not a complete safety profile. Your provider reviews your full history before prescribing and remains available throughout treatment.
Good to know
Compounded Semaglutide — questions
How fast will I see results?
Most patients notice reduced appetite within the first weeks, with measurable weight change typically developing over the first 2–3 months as the dose titrates up. Clinical trials of the branded version measured average results over more than a year — this is a long-term therapy, not a quick fix.
What is the difference between the Starter and Maintenance tiers?
They cover different concentration ranges. Starter (1–2 mg/mL, $199/mo) covers the early titration doses most patients begin with; Maintenance (3.4–5 mg/mL, $249/mo) covers the higher weekly doses your provider may move you to over time.
What happens if I stop?
Appetite generally returns toward baseline, and studies of the branded versions show weight regain is common without continued lifestyle change. Talk to your provider before stopping — tapering and transition planning matter.
Comparing options? See Compounded Tirzepatide or the side-by-side comparison.
See if you qualify.
Two-minute eligibility check. Charged only at checkout — full refund if a provider doesn't approve treatment.
Medical Disclosure
Important safety information: Compounded semaglutide and compounded tirzepatide are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Prescription weight-loss medication is only available if a licensed provider determines it is appropriate for you after reviewing your health intake. Individual results vary and no amount of weight loss is guaranteed. GLP-1 medications should be used alongside a reduced-calorie diet and increased physical activity.