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Affinity Direct

Compounded Semaglutide · 3-month starter protocols

Compounded semaglutide starter pack price for 3 months

A 3-month compounded semaglutide starter pack costs $288.15 with auto-refill ($96.05 a month) or $339 one-time ($113 a month) for the standard 0.25 → 0.5 → 1 mg weekly protocol, the same price whether it is your first order or a re-order; compounded semaglutide is not FDA-approved. The one price covers all 12 weekly doses (84 days) with the monthly dose increases included, plus a licensed provider's review, injection supplies and cold-chain shipping, and there is no membership fee.

You are charged at checkout and refunded in full if a provider does not prescribe. A starter protocol is a request, not a prescription: a licensed clinician in our partner provider network reviews your online health intake, decides whether a starter protocol is right for you and sets every dose, and may ask you to book a video visit before prescribing. Treatment is available in all 50 states.

Prices as of October 16, 2026.

Compounded semaglutide starter protocols and prices

Each protocol is a 3-month supply of 12 weekly doses (84 days) with a set weekly dose for each month, at one price. Every price is all-in: medication, licensed provider review, injection supplies and cold-chain shipping, with no membership fee. Per-month figures are the 3-month total divided by 3; it is billed as one charge. A pack costs the same each time you order it.

Compounded semaglutide 3-month starter protocols — Affinity Direct prices as of October 16, 2026.
Weekly dose scheduleWho it is for3-month pack, auto-refill3-month pack, one-time
0.25 → 0.5 → 1 mg weeklyThe standard 3-month titration — dose steps up each month, one price, titration included.$288.15$96.05 a monthCancel anytime$339$113 a monthDoes not renewStart, auto-refillStart, one-time
1.7 → 2.4 → 2.4 mg weeklyContinuation protocol — for stepping up after your first months.$381.65$127.22 a monthCancel anytime$449$149.67 a monthDoes not renewStart, auto-refillStart, one-time
2.4 mg weekly × 3 monthsTop-dose protocol — established patients at the maximum weekly dose.$381.65$127.22 a monthCancel anytime$449$149.67 a monthDoes not renewStart, auto-refillStart, one-time

The licensed provider who reviews your intake decides whether you start on a compounded semaglutide starter protocol, which one, and every dose. You may not be started on the protocol you choose, or on a starter protocol at all.

What a compounded semaglutide starter pack includes

  • One price for all 3 months

    The 12 weekly doses (84 days) of a starter protocol are priced together, with the monthly dose increases included, and ship together. The pack costs the same each time you order it.

  • No membership fee

    No membership, program or consultation fee. The protocol price is the whole price.

  • Medication, review, supplies and shipping

    Compounded semaglutide from a licensed U.S. compounding pharmacy, a licensed provider's review of your intake, syringes and alcohol prep pads, and cold-chain shipping with tracking.

  • Charged at checkout, refunded if not prescribed

    You pay at checkout. If the provider who reviews your intake does not approve treatment, your payment is refunded in full; allow 5–10 business days for it to appear.

  • Auto-refill is optional

    Subscribe & Save takes 15% off and is only on if you choose it at checkout. Pause or cancel anytime from your patient portal, with no fee. A one-time purchase never renews.

  • Available in all 50 states

    A provider licensed in your state, from our partner provider network, reviews your online intake and may ask you to book a video visit before prescribing. Approved prescriptions ship from a licensed U.S. pharmacy to all 50 states.

Compounded semaglutide starter pack: common questions

How much is a 3-month compounded semaglutide starter pack?

The standard compounded semaglutide starter pack (0.25 → 0.5 → 1 mg weekly) is $288.15 for 3 months with auto-refill ($96.05 a month) or $339 one-time ($113 a month), the same price whether it is your first order or a re-order. The 1.7 → 2.4 → 2.4 mg weekly pack is $381.65 with auto-refill or $449 one-time. The 2.4 mg weekly × 3 months pack is $381.65 with auto-refill or $449 one-time. Each price covers 12 weekly doses (84 days) with the medication, a licensed provider's review, injection supplies and cold-chain shipping, and there is no membership fee.

What happens after the 3 months?

A one-time starter pack ends after delivery: nothing renews and nothing is charged later. Re-order the starter pack at the same price, or let auto-refill continue at the final dose's 3-month price ($339.15 every 12 weeks at 1 mg after the 0.25 → 0.5 → 1 mg weekly pack; $381.65 every 12 weeks at 2.4 mg after the 1.7 → 2.4 → 2.4 mg weekly and 2.4 mg weekly × 3 months packs). With auto-refill, refills continue at the protocol's final weekly dose unless your provider changes it; each refill is charged before your current supply runs out, timed to the delivery of your last box, and a provider reviews each refill. Where that price is higher than the pack price, the difference is charged only after you confirm it at your refill check-in. If you ask to move up a dose at a refill check-in, you see the price difference and confirm it before it is charged, and you can pause or cancel anytime from your patient portal.

Is auto-refill required?

No. Auto-refill (Subscribe & Save, 15% off) is optional and only on if you choose it at checkout. Bought one-time, the standard compounded semaglutide starter pack is $339 for 3 months, billed once, and it does not renew. With auto-refill you can pause or cancel anytime from your patient portal, with no fee.

Is the dose increase included in the price?

Yes. A starter protocol is one price for all 3 months: its 12 weekly doses, including the monthly dose increases (0.25 mg in month 1, 0.5 mg in month 2 and 1 mg in month 3 for the standard compounded semaglutide starter), ship together, so a dose step within the protocol costs nothing extra. Your prescription label states the vial strength and how much to draw each week; follow it. Your provider sets the dose, and the vial strength can change if the pharmacy changes. A dose change after the protocol is priced at your refill check-in, and you confirm any difference before it is charged.

What if I'm not prescribed?

You get a full refund. You are charged at checkout; if the licensed provider who reviews your intake does not approve treatment, your payment is refunded in full (allow 5–10 business days for it to appear). A starter protocol is a request, not a prescription: the provider decides whether a compounded semaglutide starter protocol is right for you and may not start you on the one you choose.

Request a compounded semaglutide starter protocol

The eligibility check is free. You pay only if you choose a plan, and you are refunded in full if a provider does not prescribe. Your protocol choice is a request; the provider sets the actual dose. Affinity Direct is the online division of Affinity Whole Health, a Midwest clinic network founded in 2012 with 4 locations and more than 10,000 patients. Weight-loss intakes are reviewed by licensed clinicians in our partner provider network.

See if I qualify

Important safety information: Compounded semaglutide and compounded tirzepatide are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Prescription weight-loss medication is only available if a licensed provider determines it is appropriate for you after reviewing your health intake — your dose selection is a request, and the provider sets the actual dose. Individual results vary and no amount of weight loss is guaranteed. GLP-1-class medications should be used alongside a reduced-calorie diet and increased physical activity.