Compounded semaglutide · price comparison
Cheapest compounded semaglutide online, compared (October 2026)
The lowest month-to-month price for compounded semaglutide (compounded, not FDA-approved) in this comparison is SnagRx, at $99 a month at every dose, all-in; the lowest published plan rate is Astra Health's $68/mo, which requires the 12-month plan ($816 billed annually). Affinity Direct's lowest price is $96.05/mo on the 3-month starter pack (0.25 → 0.5 → 1 mg weekly) — $288.15 with auto-refill, the same price when you re-order the pack (re-order the starter pack at the same price, or let auto-refill continue at 1 mg a week ($339.15 every 3 months)); month to month it is $143.65 a month at 0.25 mg on monthly auto-refill (cancel anytime) or $169 one-time with nothing that renews, rising at 2.4 mg to $169.15 on auto-refill and $199 one-time, with no membership fee.
14 online programs in one table: what one month costs with no multi-month commitment, all-in, whether the price is the same at every dose, the lowest plan rate each publishes and what it requires, whether it renews, the refund terms and the states served — plus brand-name Wegovy self-pay as a separate reference. Every figure is read from the brand’s own pages (its semaglutide pricing page, or a policy that page links), never from a review site, a roundup or an AI answer. We do not win every row, and the rows we do not win are marked.
Prices as of 2026-10-17. Prices change often — each row links to the pages it was read from.
Important safety information: Compounded semaglutide and compounded tirzepatide are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Prescription weight-loss medication is only available if a licensed provider determines it is appropriate for you after reviewing your health intake — your dose selection is a request, and the provider sets the actual dose. Individual results vary and no amount of weight loss is guaranteed. GLP-1-class medications should be used alongside a reduced-calorie diet and increased physical activity.
One month of compounded semaglutide, month to month, all-in
Medication plus every required fee, with no multi-month commitment. Most of these are monthly subscriptions, so Affinity Direct is placed by its own monthly auto-refill price, with its one-time price beneath it. Low to high; a figure the brand’s own pages disagree on is shown last. Prices as of 2026-10-17.
The short answer
For one month, Affinity Direct is not the cheapest compounded semaglutide in this set. SnagRx $99, PreventiveMD $119, Brightmeds $129 and NexLife $139 each charge one price at every dose, and Ola Health from $129 (by dose and pharmacy) also prices one month below Affinity Direct's lowest. Affinity Direct is $143.65 a month at 0.25 mg on monthly auto-refill (cancel anytime) or $169 one-time with nothing that renews, rising at 2.4 mg to $169.15 on auto-refill and $199 one-time — lower than the cheapest flat rate (SnagRx, $99) at none of its 5 doses, on monthly auto-refill or one-time.
On a multi-month plan, Astra Health's $68/mo on the 12-month plan ($816 billed annually) is the lowest rate published. Affinity Direct's lowest is $96.05/mo on the 3-month starter pack (0.25 → 0.5 → 1 mg weekly) — $288.15 with auto-refill, the same price when you re-order the pack (re-order the starter pack at the same price, or let auto-refill continue at 1 mg a week ($339.15 every 3 months)). On three months it ranks 4 of 9, behind Ozari Health ($86/mo), SnagRx ($89/mo) and PreventiveMD ($95.34/mo); at a steady dose the 3-month auto-refill is $105.97–$127.22/mo.
Brand-name Wegovy is not one of the programs ranked here. Wegovy is a different product: it is FDA-approved, and compounded semaglutide is not a generic version of it. Self-pay through NovoCare Pharmacy it is $349 a month for the pen at every dose from 0.25 mg to 2.4 mg ($199 a month for a new patient's first 2 fills of 0.25 mg or 0.5 mg, through December 31, 2026; $399 for the 7.2 mg pen), and the Wegovy pill is $149 at 1.5 mg, $199 at 4 mg, $299 at 9 mg and 25 mg; a valid prescription is required and the provider visit is separate. NovoCare states: "Pricing to be updated after December 31, 2026"; "Novo Nordisk reserves the right to modify or cancel this program at any time"; "Eligibility and restrictions apply".
Where Affinity Direct is the better buy than the programs priced below it: a month bought once with nothing renewing ($169 one-time at 0.25 mg), where SnagRx ($99), PreventiveMD ($119), Brightmeds ($129) and NexLife ($139) sell their lower prices as plans that renew until cancelled; a full refund if a provider does not prescribe, where SnagRx ($99): Refund policy, on a provider medical disqualification: "a refund for any unused portion of the amount paid for the then-current term"; "the value of services already rendered will be deducted from your refund"; Ola Health (from $129): If found ineligible, "you will receive a full refund, minus a $50 consultation fee"; all 50 states, where Brightmeds ($129): "Offer valid only in the following states": 38 states and DC are listed — not AL, AR, CA, CT, IN, LA, MA, MI, MS, NC, NJ or SC. "Availability is subject to change". Company background: Affinity Direct is the online division of Affinity Whole Health, a Midwest clinic network established in 2012. Weight-loss intakes are reviewed by licensed providers in our partner provider network, and the medication is prepared by a state-licensed U.S. compounding pharmacy.
Compounded semaglutide at 14 online programs
Sorted by the lowest price of one month with no multi-month commitment — for Affinity Direct, monthly auto-refill at 0.25 mg. Every cell was read from the brand’s own pages, listed in the last column with the date they were read; a cell marked “Not read” was not verified.
| Program | Month-to-month, all-in | Same price at every dose? | Lowest plan rate | Buy once, nothing renews? | If a provider does not prescribe | States | Sources · read on |
|---|---|---|---|---|---|---|---|
| SnagRx | $99 flat; 1-month billing cycle | Yes "Same price no matter the dose." | $69/mo $69/mo on a 12-month billing cycle | No Refund policy: "Cancellation requests must be received at least 72 hours prior to your next billing date in order to stop the next charge." | Refund policy, on a provider medical disqualification: "a refund for any unused portion of the amount paid for the then-current term"; "the value of services already rendered will be deducted from your refund." | "This program may not be available in all states." (The semaglutide page lists no states.) | snagrx.com/semaglutide, snagrx.com/refund-policy 2026-10-17 |
| PreventiveMD | $119 flat, all-in | Yes "For our compounded medications, yes every dose is the same price." | $83/mo $83/mo on a 12-month supply ($999 paid up front; "As low as $83/mo") | No Policy: "Many of our products and services are offered as automatically renewing subscriptions"; "Your subscription continues, and your payment method is billed for each renewal, until you cancel". | Policy: "If the Provider does not approve your request, or if you cancel before the Provider’s review is complete, the authorization hold is released and you are not charged." | "This site is intended for U.S. residents only"; states served are not listed on the protocol page. | preventivemd.com/protocols/semaglutide, preventivemd.com/subscription-cancellation-refund-policy 2026-10-17 |
| Brightmeds | $129 flat; single month | Yes "Any dose, same flat price." | $99/mo $99/mo on the 3-month pack ($297 billed once) | No "Month-to-month plans automatically renew until canceled." | "If a clinician determines GLP-1 treatment isn't right for you, you'll get a 100% refund — no questions asked." | "Offer valid only in the following states": 38 states and DC are listed — not AL, AR, CA, CT, IN, LA, MA, MI, MS, NC, NJ or SC. "Availability is subject to change." | brightmeds.com/glp1 2026-10-17 |
| Ola Health | From $129 from, at the lowest doses; up to $199 by dose and pharmacy | No Rises with dose and varies by pharmacy ($129–$199). | None published 12-week plans are offered; no semaglutide per-month plan rate is published | Yes "We don’t do auto-renewals." | If found ineligible, "you will receive a full refund, minus a $50 consultation fee". | "Availability depends on which pharmacies are licensed in your state"; no state list is published. | joinolahealth.com/products/semaglutide 2026-10-17 |
| NexLife | $139 flat, all-inclusive | Yes Semaglutide row, "Same price at every dose?": "Yes". | $119/mo $119/mo on a 12-month plan ($132 and $125 on 3- and 6-month plans) | No "Plans continue monthly unless canceled." | "Any authorization charge is fully refunded if you’re not prescribed or don’t proceed." | Services "are available only to individuals physically located in U.S. states where affiliated providers are licensed and pharmacy fulfillment is permitted"; the states are not listed. | nexlife.us/pages/semaglutide-all-plans, nexlife.us/pages/glp-1-price-index 2026-10-17 |
| Affinity Direct | $143.65–$169.15 monthly auto-refill, cancel anytime · or $169–$199 one-time, nothing renews · by dose (0.25 mg → 2.4 mg weekly) | No Priced per dose; every dose is published before intake. | $96.05/mo $96.05/mo on the 3-month starter pack (0.25 → 0.5 → 1 mg weekly) — $288.15 with auto-refill, the same price when you re-order the pack (re-order the starter pack at the same price, or let auto-refill continue at 1 mg a week ($339.15 every 3 months)). Steady doses on the 3-month auto-refill are $105.97–$127.22/mo. A one-time order simply ends. | Yes Monthly auto-refill renews until cancelled; a one-time order ($169–$199) does not renew. | Charged at checkout; refunded in full if a provider does not prescribe. | All 50 states; eligibility is confirmed at intake. | affinitydirect.com/weight-loss/semaglutide 2026-10-17 |
| Astra Health | $145 flat; billed monthly | Yes "Pricing is flat at every dose." | $68/mo $68/mo on the 12-month plan ($816 billed annually) | No Refund policy: programs "are subscriptions billed upfront for the plan length you choose (monthly or multi-month) and renew automatically until cancelled." | Refund policy: "If a provider reviews your intake and does not prescribe, you receive a full refund." | "Astra operates in all 50 US states." | try-astra.com/compound-semaglutide, try-astra.com/refund-policy 2026-10-17 |
| OrderlyMeds | $149 monthly; also the price after the starter program | Not stated Not stated; the starter program is "only available for patients starting on the lowest dosage available." | $74/mo $74/mo on the starter program ("$149 total for 2 months"; new customers on the lowest dose, paid up front) | Not stated "$149/mo thereafter"; renewal and cancellation terms are not stated on the page. | Not stated on the pricing page, which links Terms & Conditions that were not reviewed here. | "Our providers are licensed to prescribe compounded medication in all 50 states." | orderlymeds.com/treatments/glp1s/compounded-glp1, orderlymeds.com 2026-10-17 |
| Gimme | $160 flat | Yes "Your price stays the same at every dose." | $109/mo $109/mo on a 6-month plan ($130/mo on 3 months) | No Plans billed per month; "There are no lock-in contracts, and you can cancel anytime from your patient portal or by messaging your care team." | "You're only charged if a clinician prescribes you — we place a temporary hold at checkout and complete payment only once you're approved." | FAQ, "Which states do you serve?": "All 50 states." | gimmecare.com/semaglutide 2026-10-17 |
| Ozari Health | $175 flat (Ozari Select, billed monthly) | Yes "Same price at every dose." | $86/mo $86/mo on Ozari One, $258 billed every 3 months (not in California); $99/mo on a $1,188 Select annual plan | No Ozari Select monthly: "Billed $175 up front, then every month." Ozari One: "Renews at $258 every 3 months." | "Full refund if a clinician does not prescribe." | Ozari Select, the month-to-month figure: "Available in all 50 states". Ozari One: "Not available in California". | ozarihealth.com/plans, ozarihealth.com 2026-10-17 |
| Rx.com | $175 flat; 1 month | Yes "Same price at every dose." "We never charge by strength." | $99/mo $99/mo on a 12-month plan ($1,188, one payment) | Yes "No automatic renewals: refills only after you check in with your care team." | "Nothing is charged until a provider approves you." Medication sales are final once shipped. | "We currently serve 49 states (all except Alaska)." | rx.com/drug/semaglutide 2026-10-17 |
| Fifty 410 | $199 one-time, no subscription | Not stated The semaglutide pricing page does not state a dose policy. | None published No semaglutide multi-month program is listed on the pricing page | Yes "No Subscription Required"; "Purchase programs as needed with complete flexibility." | "Pay only if prescribed by a licensed provider." | The semaglutide pricing page does not list the states served. | fifty410.com/pricing/semaglutide 2026-10-17 |
| Embody | $69 advertised advertised on the homepage under a sale banner; terms list $199 flat or $99 then $299 | Yes "Your price does not increase if your dose changes within the same medication." | $149/mo $149/month on a 12-month Flat Program bundle, per the terms page | No "You may cancel your subscription at any time before your next medication shipment to avoid being charged for the upcoming billing cycle." | Refund policy, on a provider medical disqualification: "a refund for any unused portion of the amount paid for the then-current term"; "the value of services already rendered will be deducted from your refund." | Terms §V: "The Services are currently available to individuals located in certain states. To see the list of current states, please contact customer service" by email. | joinem.co, joinem.co/pages/terms-conditions, joinem.co/pages/refund-policy 2026-10-17 |
| Mochi Health | Not published not published as one all-in month: medication "$146 per 3-month supply, billed once" plus the membership | No "Price varies based on the dose your provider prescribes." | None published Not published as an all-in per-month rate | No Membership "$0 first month, then $79/month"; medication "$146 per 3-month supply, billed once". | The semaglutide page links a "Refunds" page that was not reviewed here. | The semaglutide page does not list the states served. | joinmochi.com/lp/compounded-semaglutide 2026-10-17 |
“Month-to-month, all-in” is the published price of one month with no multi-month commitment, medication plus any required membership; for most programs that month is a subscription that renews, and the “Buy once” column says which. Affinity Direct’s row shows both of its billing choices. “Lowest plan rate” is the lowest per-month figure the brand publishes on any prepaid, multi-month or starter plan, with what it requires beside it. A figure a brand shows only after a quiz or at checkout counts as not published.
Affinity Direct compounded semaglutide price by weekly dose
Every Affinity Direct semaglutide dose, one-time and on auto-refill, with medication, provider review, injection supplies and cold shipping included. Compounded semaglutide is not FDA-approved. The provider sets the actual dose.
| Weekly dose | One month, one-time | One month, auto-refill | 3 months on auto-refill | 3 months, one-time |
|---|---|---|---|---|
| 0.25 mg weekly | $169 | $143.65 | $105.97/mo $317.90 every 3 months | $374 |
| 0.5 mg weekly | $174 | $147.90 | $107.39/mo $322.15 every 3 months | $379 |
| 1 mg weekly | $179 | $152.15 | $113.05/mo $339.15 every 3 months | $399 |
| 1.7 mg weekly | $189 | $160.65 | $121.55/mo $364.65 every 3 months | $429 |
| 2.4 mg weekly | $199 | $169.15 | $127.22/mo $381.65 every 3 months | $449 |
| Starter protocol: 0.25 → 0.5 → 1 mg weekly | Sold as 3 months | Sold as 3 months | $96.05/mo $288.15 on the 3-month starter pack ($288.15, the same price when you re-order the pack) | $339 |
| Starter protocol: 1.7 → 2.4 → 2.4 mg weekly | Sold as 3 months | Sold as 3 months | $127.22/mo $381.65 on the 3-month starter pack ($381.65, the same price when you re-order the pack) | $449 |
| Starter protocol: 2.4 mg weekly × 3 months | Sold as 3 months | Sold as 3 months | $127.22/mo $381.65 on the 3-month starter pack ($381.65, the same price when you re-order the pack) | $449 |
Brand-name Wegovy, for reference
Wegovy is a different product: it is FDA-approved, and compounded semaglutide is not a generic version of it, so its price is not a like-for-like comparison. Self-pay through NovoCare Pharmacy it is $349 a month for the pen at every dose from 0.25 mg to 2.4 mg ($199 a month for a new patient's first 2 fills of 0.25 mg or 0.5 mg, through December 31, 2026; $399 for the 7.2 mg pen), and the Wegovy pill is $149 at 1.5 mg, $199 at 4 mg, $299 at 9 mg and 25 mg; a valid prescription is required and the provider visit is separate. NovoCare states: "Pricing to be updated after December 31, 2026"; "Novo Nordisk reserves the right to modify or cancel this program at any time"; "Eligibility and restrictions apply". A month is one box of 4 pens, or one bottle of 30 tablets. Read on novocare.com on 2026-10-17. novocare.com
Who wins what
Honest verdicts, including the ones that go against us.
$99 at every dose from SnagRx; the flat-rate programs below Affinity Direct's lowest one-month price are SnagRx $99, PreventiveMD $119, Brightmeds $129 and NexLife $139. Affinity Direct is $143.65 a month at 0.25 mg on monthly auto-refill (cancel anytime) or $169 one-time with nothing that renews, rising at 2.4 mg to $169.15 on auto-refill and $199 one-time — lower than $99 at none of its 5 doses, on monthly auto-refill or one-time. Not ranked, because the brand's own pages disagree: Embody — $69 advertised on the homepage under a sale banner; terms list $199 flat or $99 then $299.
Astra Health: $68/mo on the 12-month plan ($816 billed annually). Then SnagRx: $69/mo on a 12-month billing cycle; OrderlyMeds: $74/mo on the starter program ("$149 total for 2 months"; new customers on the lowest dose, paid up front); PreventiveMD: $83/mo on a 12-month supply ($999 paid up front; "As low as $83/mo"); Ozari Health: $86/mo on Ozari One, $258 billed every 3 months (not in California); $99/mo on a $1,188 Select annual plan. Affinity Direct's lowest is $96.05/mo on the 3-month starter pack (0.25 → 0.5 → 1 mg weekly) — $288.15 with auto-refill, the same price when you re-order the pack (re-order the starter pack at the same price, or let auto-refill continue at 1 mg a week ($339.15 every 3 months)); no 12-month prepayment is offered or required.
Ozari Health $86/mo ($258) · SnagRx $89/mo · PreventiveMD $95.34/mo ($286) · Affinity Direct $96.05/mo on the 3-month starter pack ($288.15, the same price when you re-order the pack) · Brightmeds $99/mo ($297) · Gimme $130/mo · NexLife $132/mo · Rx.com $165/mo ($495) · Embody $169/mo. Affinity Direct ranks 4 of 9 on its 3-month starter pack; at a steady dose its 3-month auto-refill is $105.97–$127.22/mo.
NexLife, Brightmeds, SnagRx, Embody, PreventiveMD, Gimme, Astra Health, Ozari Health and Rx.com each state that their semaglutide price does not rise with dose. Affinity Direct, Ola Health and Mochi Health price by dose; Fifty 410 and OrderlyMeds do not say on the semaglutide pages read. Affinity Direct's ladder runs $143.65–$169.15 on monthly auto-refill and $169–$199 one-time.
Affinity Direct ($169 one-time at 0.25 mg, refunded in full if not prescribed), Ola Health ("We don’t do auto-renewals" — from $129 a month), Fifty 410 ("No Subscription Required"; "Purchase programs as needed with complete flexibility" — $199 a month) and Rx.com ("No automatic renewals: refills only after you check in with your care team" — $175 a month) sell a month of semaglutide without a recurring charge. NexLife, Brightmeds, SnagRx, Embody, PreventiveMD, Gimme, Astra Health, Ozari Health and Mochi Health sell theirs as plans or subscriptions that continue until cancelled. OrderlyMeds does not state renewal terms on the pages read.
Affinity Direct (Charged at checkout; refunded in full if a provider does not prescribe.); NexLife ("Any authorization charge is fully refunded if you’re not prescribed or don’t proceed."); Brightmeds ("If a clinician determines GLP-1 treatment isn't right for you, you'll get a 100% refund — no questions asked."); PreventiveMD (Policy: "If the Provider does not approve your request, or if you cancel before the Provider’s review is complete, the authorization hold is released and you are not charged."); Gimme ("You're only charged if a clinician prescribes you — we place a temporary hold at checkout and complete payment only once you're approved."); Fifty 410 ("Pay only if prescribed by a licensed provider."); Astra Health (Refund policy: "If a provider reviews your intake and does not prescribe, you receive a full refund."); Ozari Health ("Full refund if a clinician does not prescribe."); Rx.com ("Nothing is charged until a provider approves you." Medication sales are final once shipped.). Partial refund: SnagRx (Refund policy, on a provider medical disqualification: "a refund for any unused portion of the amount paid for the then-current term"; "the value of services already rendered will be deducted from your refund."); Embody (Refund policy, on a provider medical disqualification: "a refund for any unused portion of the amount paid for the then-current term"; "the value of services already rendered will be deducted from your refund."); Ola Health (If found ineligible, "you will receive a full refund, minus a $50 consultation fee".). Not stated or not reviewed here: Mochi Health (The semaglutide page links a "Refunds" page that was not reviewed here.); OrderlyMeds (Not stated on the pricing page, which links Terms & Conditions that were not reviewed here.).
Affinity Direct offers GLP-1 weight-loss treatment in all 50 states; eligibility is confirmed at intake. Also stating all 50: Gimme (FAQ, "Which states do you serve?": "All 50 states"), Astra Health ("Astra operates in all 50 US states"), Ozari Health (Ozari Select, the month-to-month figure: "Available in all 50 states". Ozari One: "Not available in California") and OrderlyMeds ("Our providers are licensed to prescribe compounded medication in all 50 states"). Fewer: Brightmeds ("Offer valid only in the following states": 38 states and DC are listed — not AL, AR, CA, CT, IN, LA, MA, MI, MS, NC, NJ or SC. "Availability is subject to change"); Rx.com ("We currently serve 49 states (all except Alaska)"). NexLife, SnagRx, Embody, Ola Health, PreventiveMD, Fifty 410 and Mochi Health do not say they serve all 50 states on the semaglutide pages read.
Every program here is all-in except Mochi Health, which bills a $79/mo membership separately from medication priced by dose.
No compounded program here is FDA-approved. Wegovy is a different product: it is FDA-approved, and compounded semaglutide is not a generic version of it. Self-pay through NovoCare Pharmacy it is $349 a month for the pen at every dose from 0.25 mg to 2.4 mg ($199 a month for a new patient's first 2 fills of 0.25 mg or 0.5 mg, through December 31, 2026; $399 for the 7.2 mg pen), and the Wegovy pill is $149 at 1.5 mg, $199 at 4 mg, $299 at 9 mg and 25 mg; a valid prescription is required and the provider visit is separate. NovoCare states: "Pricing to be updated after December 31, 2026"; "Novo Nordisk reserves the right to modify or cancel this program at any time"; "Eligibility and restrictions apply".
What each advertised semaglutide rate requires
The headline rate each brand leads with, and the conditions on its own page.
- NexLife — advertises $139/mo at every dose (from $119/mo on a 12-month plan)
- The $139 is the month-to-month plan, "all-inclusive", with "no membership fee". The $132 / $125 / $119 rates are the 3-, 6- and 12-month plans ("Longer plans cost less and stay flat").Read 2026-10-17 at nexlife.us/pages/semaglutide-all-plans, nexlife.us/pages/glp-1-price-index
- Brightmeds — advertises from $99/mo semaglutide (3-month pack); $129 month-to-month
- The $99/mo requires the 3-month pack, "$297 billed once"; "$129 for a single month". Month-to-month plans "automatically renew until canceled". "New customers who are new to GLP-1 treatment begin at the lowest available dose"; "Customers currently taking a GLP-1 medication or transferring an existing prescription should contact customer support" for pricing.Read 2026-10-17 at brightmeds.com/glp1
- SnagRx — advertises from $69/mo (12-month billing cycle); $99 month-to-month
- Per month by billing cycle: 1-month $99 · 3-month $89 · 6-month $79 · 12-month $69. "No membership or hidden fees." The semaglutide page states the program "may not be available in all states".Read 2026-10-17 at snagrx.com/semaglutide, snagrx.com/refund-policy
- Embody — advertises "flat rate at $69/month" (homepage, under a "Pre-Black Friday Sale" banner)
- The homepage rate is advertised under a "Pre-Black Friday Sale Promo Applied" banner. The terms page (last updated April 24, 2026) lists a semaglutide injection on the Start Program at $99 for month one then $299/month, and on the Flat Program at $199/month month-to-month ($169, $159 and $149/month on 3-, 6- and 12-month bundles). Which applies is shown at checkout.Read 2026-10-17 at joinem.co, joinem.co/pages/terms-conditions, joinem.co/pages/refund-policy
- Ola Health — advertises from $129/month (lowest doses at the lowest-priced pharmacies)
- "Priced from $129–$199/month. Availability depends on which pharmacies are licensed in your state." The same 0.2 mg dose is $129 or $149 depending on the pharmacy.Read 2026-10-17 at joinolahealth.com/products/semaglutide
- PreventiveMD — advertises as low as $83/mo, all-in (12-month supply)
- The $83/mo is the 12-month supply, $999 paid up front; the 6-month supply is $536 and the 3-month supply $286. A single month is $119. "Longer plans come at a lower monthly rate and are paid upfront."Read 2026-10-17 at preventivemd.com/protocols/semaglutide, preventivemd.com/subscription-cancellation-refund-policy
- Gimme — advertises from $109/mo (6-month plan); $160 month-to-month
- The $109 is the 6-month plan and $130 the 3-month plan; one month is $160. "Cancel anytime."Read 2026-10-17 at gimmecare.com/semaglutide
- Fifty 410 — advertises $199/month
- "$199/month" — "$199 total" for a 1-month supply, with "Free overnight/2-day shipping". "No Subscription Required"; "Pay only if prescribed by a licensed provider".Read 2026-10-17 at fifty410.com/pricing/semaglutide
- Astra Health — advertises from $68/mo semaglutide (12-month plan)
- The $68/mo requires the 12-month plan, "billed annually at $816 total"; billed monthly the same medication is "$145/month".Read 2026-10-17 at try-astra.com/compound-semaglutide, try-astra.com/refund-policy
- Ozari Health — advertises $86/mo semaglutide (Ozari One, billed $258 every 3 months)
- The $86/mo is Ozari One, "Billed $258 up front, then every 3 months", and is "Not available in California". Ozari Select ("Available in all 50 states") is $175 billed monthly, $145/mo quarterly ($435), $120/mo semi-annually ($720) and $99/mo annually ($1,188).Read 2026-10-17 at ozarihealth.com/plans, ozarihealth.com
- Mochi Health — advertises medication "$146 per 3-month supply, billed once" + membership
- "Requires a Mochi Health Membership. Cost of medication not included in Mochi Health Membership Fee." Membership: "$0 first month, then $79/month". The medication price varies with the prescribed dose.Read 2026-10-17 at joinmochi.com/lp/compounded-semaglutide
- Rx.com — advertises from $99/mo (12-month plan); $175 for one month
- The $99/mo is the 12-month plan, "$1,188" in "one payment". 3 months is $495 ($165/mo) and 6 months $875 ($146/mo); one month is $175. "There are no visit fees, membership fees, dose upcharges or shipping charges added at checkout."Read 2026-10-17 at rx.com/drug/semaglutide
- OrderlyMeds — advertises "Get started for as little as $74 a month"
- The $74/mo is the starter program — "$149 total for 2 months", "only available for patients starting on the lowest dosage available", "Pay upfront in full" — then "$149/mo thereafter". "Monthly plans are available for $149 per month for those currently taking a GLP-1 medication and for returning customers."Read 2026-10-17 at orderlymeds.com/treatments/glp1s/compounded-glp1, orderlymeds.com
Common questions
What is the cheapest compounded semaglutide online?
Month to month, with no multi-month commitment, the lowest published all-in price in this comparison (checked 2026-10-17) is $99 at every dose, from SnagRx. The flat-rate programs priced below Affinity Direct's lowest one-month price are SnagRx $99, PreventiveMD $119, Brightmeds $129 and NexLife $139; Ola Health from $129 (by dose and pharmacy) also prices one month below it. On a prepaid plan, the lowest published rate is Astra Health's $68/mo on the 12-month plan ($816 billed annually). Affinity Direct is $143.65 a month at 0.25 mg on monthly auto-refill (cancel anytime) or $169 one-time with nothing that renews, rising at 2.4 mg to $169.15 on auto-refill and $199 one-time, with no membership fee, or $96.05/mo on the 3-month starter pack (0.25 → 0.5 → 1 mg weekly) — $288.15 with auto-refill, the same price when you re-order the pack (re-order the starter pack at the same price, or let auto-refill continue at 1 mg a week ($339.15 every 3 months)). Compounded semaglutide is not FDA-approved.
How much does semaglutide cost per month online without insurance?
In this comparison, one month of compounded semaglutide costs $99–$199 all-in with no multi-month commitment (checked 2026-10-17), and prepaid plans go as low as $68/mo. Affinity Direct's compounded semaglutide is $143.65–$169.15 a month on monthly auto-refill or $169–$199 one-time for one month, by dose, or $96.05/mo on the 3-month starter pack ($288.15, the same price when you re-order the pack) — medication, provider review, injection supplies and cold shipping included. Brand-name Wegovy is a different, FDA-approved product, and compounded semaglutide is not a generic version of it. Self-pay through NovoCare Pharmacy it is $349 a month for the pen at every dose from 0.25 mg to 2.4 mg ($199 a month for a new patient's first 2 fills of 0.25 mg or 0.5 mg, through December 31, 2026; $399 for the 7.2 mg pen), and the Wegovy pill is $149 at 1.5 mg, $199 at 4 mg, $299 at 9 mg and 25 mg; a valid prescription is required and the provider visit is separate. NovoCare states: "Pricing to be updated after December 31, 2026"; "Novo Nordisk reserves the right to modify or cancel this program at any time"; "Eligibility and restrictions apply".
Which online semaglutide programs have no membership fee?
Every program in this comparison prices semaglutide all-in with no separate membership fee except Mochi Health, which requires a $79/mo membership billed separately from medication priced by dose. Affinity Direct charges no membership, consultation or shipping fee: the published price covers the medication, the licensed provider review, injection supplies and cold-chain shipping, and there is nothing to schedule up front (a licensed provider in our partner provider network reviews your online intake and may ask for a short video visit).
Is semaglutide or tirzepatide cheaper online?
Semaglutide, at most programs. At Affinity Direct, compounded semaglutide is $169–$199 one-time for one month against $174–$269 for compounded tirzepatide, and the lowest effective auto-refill rate is $96.05/mo on the 3-month starter pack ($288.15, the same price when you re-order the pack), against $120.14/mo for tirzepatide on its 3-month auto-refill ($360.40 every 3 months). Of the 9 other programs here that publish both month-to-month prices, semaglutide is cheaper at 7, the same starting price at Ola Health (where the price rises with dose) and the same one-month price at Fifty 410. Which medication is appropriate is a clinical decision a licensed provider makes after reviewing your health history; price is only one difference between them.
What is the cheapest legitimate way to get semaglutide without insurance in 2026?
Both routes need a prescription from a licensed provider. Wegovy is a different product: it is FDA-approved, and compounded semaglutide is not a generic version of it. Self-pay through NovoCare Pharmacy it is $349 a month for the pen at every dose from 0.25 mg to 2.4 mg ($199 a month for a new patient's first 2 fills of 0.25 mg or 0.5 mg, through December 31, 2026; $399 for the 7.2 mg pen), and the Wegovy pill is $149 at 1.5 mg, $199 at 4 mg, $299 at 9 mg and 25 mg; a valid prescription is required and the provider visit is separate. NovoCare states: "Pricing to be updated after December 31, 2026"; "Novo Nordisk reserves the right to modify or cancel this program at any time"; "Eligibility and restrictions apply". Compounded semaglutide is prepared by a state-licensed U.S. compounding pharmacy against an individual prescription and is not FDA-approved; month to month it runs $99–$199 all-in in this comparison. At Affinity Direct it is $143.65 a month on monthly auto-refill or $169 one-time at 0.25 mg, with the provider review included, charged at checkout and refunded in full if a provider does not prescribe.
Does Affinity Direct charge a membership or consultation fee for semaglutide?
No. The published price covers the medication, the licensed provider review, injection supplies and cold-chain shipping. There is no membership fee, no separate consultation fee and no shipping charge. Auto-refill saves 15% and is optional; a one-time purchase does not auto-renew.
Do I have to subscribe to get the lowest semaglutide price?
At Affinity Direct, the lowest one-month price ($143.65 at 0.25 mg) is monthly auto-refill, which can be cancelled at any time; a one-time month is $169 with no renewal. The lower $96.05/mo rate is on the 3-month starter pack ($288.15, the same price when you re-order the pack), on the optional 3-month auto-refill. Among the other programs here, Ola Health, Fifty 410 and Rx.com sell semaglutide without a recurring charge; the lowest advertised rates — Astra Health at $68/mo, SnagRx at $69/mo, OrderlyMeds at $74/mo, PreventiveMD at $83/mo — require a prepaid plan, a multi-month billing cycle or a starter program.
Is Rx.com semaglutide really $99 a month?
On its 12-month plan. Read on rx.com on 2026-10-17, compounded semaglutide is $175 for one month, $165/mo on 3 months ($495) and $99/mo on a 12-month plan ($1,188, one payment), the same price at every dose. On renewal it states: "No automatic renewals: refills only after you check in with your care team." On states: "We currently serve 49 states (all except Alaska)." Affinity Direct's comparable figures are $143.65 a month on monthly auto-refill or $169 one-time for one month at 0.25 mg, and $96.05/mo on the 3-month starter pack ($288.15, the same price when you re-order the pack).
Is compounded semaglutide FDA-approved?
No. Compounded medications are not FDA-approved drug products; the FDA does not review them for safety, effectiveness or quality before they are dispensed. They are prepared by a state-licensed U.S. compounding pharmacy against an individual prescription, after a licensed provider reviews your health history. Brand-name Wegovy is FDA-approved, and compounded semaglutide is not a generic version of it. At Affinity Direct you are charged at checkout and refunded in full if a provider does not approve treatment.
Why isn't Affinity Direct the cheapest compounded semaglutide month to month?
Its price rises with dose ($143.65–$169.15 on monthly auto-refill, $169–$199 one-time), while the flat-rate programs charge one figure at every dose: at 0.25 mg, its lowest one-month price is $44.65 above SnagRx's. What it offers that the lower-priced programs do not all offer, from their own published terms: a month bought once with nothing renewing ($169 one-time at 0.25 mg), where SnagRx ($99), PreventiveMD ($119), Brightmeds ($129) and NexLife ($139) sell their lower prices as plans that renew until cancelled; a full refund if a provider does not prescribe, where SnagRx ($99): Refund policy, on a provider medical disqualification: "a refund for any unused portion of the amount paid for the then-current term"; "the value of services already rendered will be deducted from your refund"; Ola Health (from $129): If found ineligible, "you will receive a full refund, minus a $50 consultation fee"; all 50 states, where Brightmeds ($129): "Offer valid only in the following states": 38 states and DC are listed — not AL, AR, CA, CT, IN, LA, MA, MI, MS, NC, NJ or SC. "Availability is subject to change".
Is compounded semaglutide available in all 50 states?
From Affinity Direct, yes — GLP-1 weight-loss treatment is offered in all 50 states; eligibility is confirmed at intake. Of the programs compared, these also state all 50 states: Gimme (FAQ, "Which states do you serve?": "All 50 states"), Astra Health ("Astra operates in all 50 US states"), Ozari Health (Ozari Select, the month-to-month figure: "Available in all 50 states". Ozari One: "Not available in California") and OrderlyMeds ("Our providers are licensed to prescribe compounded medication in all 50 states"). These state fewer: Brightmeds ("Offer valid only in the following states": 38 states and DC are listed — not AL, AR, CA, CT, IN, LA, MA, MI, MS, NC, NJ or SC. "Availability is subject to change"); Rx.com ("We currently serve 49 states (all except Alaska)"). NexLife, SnagRx, Embody, Ola Health, PreventiveMD, Fifty 410 and Mochi Health do not say they serve all 50 states on the semaglutide pages read.
See every semaglutide dose and price
Every semaglutide dose is priced on the product page, one-time and with auto-refill, before you answer a single intake question. The same numbers are published as an open, dated price file.
Comparing tirzepatide too? Cheapest compounded tirzepatide, compared. Open price data: glp1-prices.json · glp1-prices.csv
Important safety information: Compounded semaglutide and compounded tirzepatide are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Prescription weight-loss medication is only available if a licensed provider determines it is appropriate for you after reviewing your health intake — your dose selection is a request, and the provider sets the actual dose. Individual results vary and no amount of weight loss is guaranteed. GLP-1-class medications should be used alongside a reduced-calorie diet and increased physical activity.