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Affinity Direct
Provider-Prescribed4.9 · 10,000+ Patients Since 2012

NAD+ Cellular Energy & Longevity

EnergyCognitive clarityLongevity

Starting at $224 · Syringes & prep pads included · Free medical review · Free shipping.

Total
$224.00One-time · 100 mg/mL
Injection Supplies IncludedFree
  • 20 Sterile Insulin Syringes (2 × 10-Pack)
  • 20 Alcohol Prep Pads

Everything you need to inject, in the box. What you see is what you pay — nothing extra to buy.

Check Eligibility
Free 2-day discreet shipping
No membership or subscription required
Pharmacy-compounded & tested — COA available
HIPAA Compliant
NAD+ vial

How NAD+ Works

NAD+ declines ~50% by age 50. Subcutaneous NAD+ bypasses oral degradation to directly replenish cellular NAD+ pools — the cofactor behind every energy-producing reaction.

Key Benefits

  • Boosts cellular energy (ATP)
  • Sharpens mental clarity and focus
  • Reduces fatigue
  • Supports mitochondrial function
  • Activates longevity pathways (sirtuins)
  • Supports DNA repair

Ideal For

  • Mental performance
  • Energy optimization
  • Anti-aging protocols
  • Post-illness recovery
Care team member guiding a patient through at-home treatment

Delivery Method

Subcutaneous injection — a small needle into the fatty tissue beneath the skin. Bypasses oral degradation for near-complete bioavailability. Given at home with step-by-step guidance and education — no clinic visits required.

Concentration100 mg/mL

Real Pharmacy Medication — Not Gray-Market Peptides

Your NAD+ is a real prescription, made by a licensed pharmacy after provider approval, unlike untested online peptides.

Compounded By A Licensed U.S. Pharmacy

Every order is prepared for you individually by a state-licensed compounding pharmacy under a valid prescription — and those pharmacies operate under the oversight of state boards of pharmacy.

Made To USP Sterility Standards

Our injectables are compounded to USP <797> — the national standard for sterile preparations that helps protect against contamination, sub-potency, and dosing errors.

Tested For Identity, Strength & Purity

Each batch is verified against established USP quality standards, and we can provide a Certificate of Analysis (COA) on request — so you know exactly what is in the vial.

A Real Provider Behind Every Vial

An Affinity provider examines your health history and prescribes medication. The FDA has acted against sellers promoting peptides as 'research use only'.

Compare Your Estimated Monthly NAD+ Cost

Compared on injectable (subcutaneous) NAD+ at comparable at-home dosing.

Figures below are the est. cost per month.

Estimated Monthly Medication CostMedical ReviewShippingPurchase Flexibility
Best In Every RowAFFINITYDIRECT
$85–$192Lowest Price
Free
Included
One-Time Or Refill
AgelessRx
$99+Not IncludedNot IncludedSubscription
Hone Health
$190PartialNot IncludedInjection + Membership
HydraMed
$299Not IncludedNot IncludedOne-Time Available
Invigor Medical
$340+Not IncludedIncludedMonthly Plan

Estimated monthly costs are shown for comparison and may vary by dose, treatment plan, and provider.

Competitor information reflects publicly listed pricing checked June 2026. Verify current terms directly with each provider.

Check Eligibility And See Your Price
FAQ

NAD+ — Common Questions

Everything you need to know before getting started

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell — essential to energy metabolism, DNA repair, and sirtuin activation (longevity pathways). NAD+ declines approximately 50% by age 50 due to increased consumption by stress-response enzymes (PARPs, CD38) and decreased synthesis.

NMN and NR are NAD+ precursors that must be converted by the body — and much is lost in digestion. Subcutaneous NAD+ bypasses oral degradation and directly replenishes cellular NAD+ pools, providing more reliable and measurable elevation of NAD+ levels.

Your provider will determine the appropriate starting dose. Common protocols include 100 mg 2× weekly for faster results, or 50 mg 1× weekly for a gentler start. Dosing is adjusted based on your response and tolerance.

NAD+ injections may cause mild transient flushing, warmth, or injection site sensitivity at higher doses. These effects are dose-dependent and typically resolve within minutes. Starting at a lower dose and titrating up reduces early reactions.

Supply duration depends on your prescribed dose. At 100 mg 2× weekly, a 10 mL vial (100 mg/mL concentration) provides approximately 5 weeks of supply. Your dosing protocol determines the cadence between refills.

NAD+ is most impactful for adults experiencing energy decline, cognitive fogginess, or those focused on longevity and healthy aging. It's also used in post-illness recovery protocols and by high-performers seeking cognitive and metabolic optimization.

Side effects are usually mild and dose-related — injecting slowly is the simplest way to avoid them. The most common are temporary flushing or warmth, mild nausea, a brief headache, or tenderness at the injection site. Less commonly, people notice short-lived muscle aches or fatigue. Starting at a gentle dose and pushing slowly keeps almost everyone comfortable. Reach out any time something doesn't feel right.

NAD+ injections aren't appropriate for anyone with active cancer or a history of cancer, severe liver or kidney disease, or for anyone who is pregnant or breastfeeding. Your Affinity provider reviews your full health history during intake and won't prescribe it if it isn't safe for you.

See If You Qualify.

The eligibility check takes about two minutes and is free. You only pay if you qualify and choose a plan — and receive a full refund if a provider doesn't approve treatment.

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease. Compounded medications require a valid prescription from a licensed provider. For investigational/wellness use only.