Peptide therapy comparison
Affinity Direct vs Hone Health
Hone Health is a membership-based telehealth platform focused on men’s hormones and longevity, where treatment pricing is built around an ongoing membership. Affinity Direct is the online arm of Affinity Whole Health — a real Midwest clinic network operating since 2012 — with transparent one-time vial pricing, no membership fee, and free injection supplies with every order.
One-time vial prices, published up front.
Free shipping and free injection supplies included. No membership or consultation fees. Your card is charged at checkout, with a full refund if a licensed provider doesn't approve treatment.
| Affinity Direct | Hone Health | |
|---|---|---|
| What it is | Online arm of a real Midwest clinic network — 4 locations, 10,000+ patients since 2012 | Telehealth-only men’s health platform — no physical clinics of its own |
| Membership | No membership fee — pay only for your medication | Membership required; treatment pricing includes ongoing membership fees |
| Pricing | Published up front: glutathione $349 (30 mL), MIC+B12 $349 (30 mL), NAD+ from $224, sermorelin from $274, PT-141 from $249 — one-time vials | Listed with required membership rolled in — e.g. glutathione $115/mo and NAD+ $190/mo as of June 2026 |
| Ordering model | One-time vial purchases — reorder only when you want to | Ongoing monthly plans tied to the membership |
| Injection supplies & shipping | Free shipping and free injection supplies (syringes + alcohol prep pads) with every vial | Varies by plan |
| Provider review | Licensed provider reviews your intake within 24 hours — full refund if not approved | Licensed provider consultation; lab testing emphasized |
| States served | OH, IN, IL, AZ, PA (expanding) | Broad national coverage |
Competitor details reflect publicly listed information as of June 2026 and may change; membership, consultation, or plan fees may apply. Affinity Direct prices are current published pricing.
Hone Health fits if you want an ongoing membership built around lab panels and hormone optimization. If you want peptide therapy with transparent one-time pricing from a real clinic — no membership fee, free supplies, and a licensed provider review before any charge — Affinity Direct is the stronger fit.
Explore peptide therapyCommon questions
Does Affinity Direct charge a membership fee for peptide therapy?
No. Affinity Direct has no membership or subscription fee. You pay a one-time price per order — glutathione $349 (30 mL), MIC+B12 $349 (30 mL), NAD+ from $224, sermorelin from $274, PT-141 from $249 — with free shipping and free injection supplies included.
How is Affinity Direct different from Hone Health?
Hone Health is a telehealth-only platform where treatment pricing is built around a required membership. Affinity Direct is the online division of Affinity Whole Health, a real Midwest clinic network with 4 locations and 10,000+ patients since 2012, offering one-time vial pricing with no membership fee.
Is a prescription required for peptides from Affinity Direct?
Yes. Every order is reviewed by a licensed provider, typically within 24 hours. Your card is charged at checkout, and if the provider determines treatment is not appropriate, you receive a full refund. Compounded medications require a valid prescription and are filled by a regulated U.S. compounding pharmacy.
Which states does Affinity Direct serve?
Affinity Direct serves all 50 states — Ohio, Indiana, Illinois, Arizona, and Pennsylvania through the Affinity clinic network, and every other state through its licensed partner provider network.
Real clinic. Real prices. No membership.
Peptide vials from $224, one-time · Free shipping + injection supplies · Licensed provider review, typically under 24 hours.
Compounded medications require a valid prescription from a licensed provider and are dispensed only when a provider determines treatment is appropriate. Individual results vary.